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PMWS Research Archives
Published Jan 2008: J Gen Virol 89 (2008), 177-187; DOI 10.1099/vir.0.83280-0Antigenic differences among porcine circovirus type 2 strains, as demonstrated by the use of monoclonal antibodies
D. J. Lefebvre, S. Costers, J. Van Doorsselaere, G. Misinzo, P. L. Delputte and H. J. Nauwynck
This study examined whether antigenic differences among porcine circovirus type 2 (PCV-2) strains could be detected using monoclonal antibodies (mAbs). A subtractive immunization protocol was used for the genotype 2 post-weaning multisystemic wasting...
Published Jan 2008: Journal of Virological Methods - Volume 147, Issue 1, January 2008, Pages 61-66
Thermal stability of porcine circovirus type 2 in cell culture
Mark A. O’Dea, Andrew P. Hughes, Linda J. Davies, Jillian Muhling, Ross Buddle and G.E. Wilcox
Received 2 May 2007; revised 25 July 2007; accepted 30 July 2007. Available online 21 September 2007. International trade in pig meat has resulted in some countries placing restrictions on the importation of pig meat, with requirements for cooking...
Published Jan 2008: Journal of Biotechnology - Volume 133, Issue 1, 1 January 2008, Pages 58-64
Expression of the porcine circovirus type 2 capsid protein subunits and application to an indirect ELISA
Pei-Ching Wu, Maw-Sheng Chien, Yu-Yao Tseng, Jiarong Lina Wei-Li Lin, Cheng-Yao Yang and Chienjin Huang
Received 18 April 2007; revised 24 August 2007; accepted 19 September 2007. Available online 2 October 2007. Porcine circovirus type 2 (PCV2) is considered to be associated with post-weaning multisystemic wasting syndrome (PMWS), which is a newly...
Published Dec 2007: New Zealand Veterinary Journal, Volume 55, Number 6, December 2007 , pp. 346-352(7)
Descriptive summary of an outbreak of porcine post-weaning multisystemic wasting syndrome (PMWS) in New Zealand
Neumann, E.J.; Dobbinson, S.S.A.; Welch, E.B.M.; Morris, R.S.
CASE HISTORY: Investigations were conducted to determine the cause of an acute, multi-farm outbreak of porcine respiratory disease that included diarrhoea and subsequent loss of body condition in affected pigs. A definition for post-weaning multisystemic...
Published Dec 2007: Virology - Volume 369, Issue 2, 20 December 2007, Pages 423-430
Enhanced replication of porcine circovirus type 2 (PCV2) in a homogeneous subpopulation of PK15 cell line
Yu Zhu, Adeline Lau, Jennifer Lau, Qiang Jia, Anbu K. Karuppannan and Jimmy Kwang
Received 4 July 2007; revised 27 July 2007; accepted 7 August 2007. Available online 24 September 2007. Post-weaning multi-systemic wasting syndrome (PMWS) has emerged as a major disease that poses a significant threat to the economics of global...
Published Dec 2007: Veterinary Microbiology. Volume 125, Issues 3-4, 15 December 2007, Pages 244-255
Detection of neutralizing antibodies in postweaning multisystemic wasting syndrome (PMWS)-affected and non-PMWS-affected pigs.
Fort M, Olvera A, Sibila M, Segalés J, Mateu E.
Received 2 January 2007; revised 1 June 2007; accepted 5 June 2007. Available online 13 June 2007 The notion that postweaning multisystemic wasting syndrome (PMWS)-affected pigs develop an impaired humoral response against porcine circovirus type...
Published Dec 2007: Virus Genes. 2007 Dec;35(3):619-27. Epub 2007 Sep 13.
Genetic characterization of porcine circovirus type 2 (PCV2) from pigs in high-seroprevalence areas in southeastern China
Jiangbing Shuai, Wei Wei, Xiaoliang Li, Ning Chen, Zhanfeng Zhang, Xueyan Chen and Weihuan Fang
Received: 19 April 2007 Accepted: 16 May 2007 Published online: 13 September 2007 Increasing evidences indicate that porcine circovirus type 2 (PCV2) is the causative agent of the post-weaning multisystemic wasting syndrome (PMWS). In this study, the...
Published Dec 2007: Veterinary Quarterly - Volume 29 (2007), Issue 4
Postweaning multisystemic wasting syndrome (PMWS) in Sweden from an exotic to an endemic disease.
Wallgren P, Belák K, Ehlorsson CJ, Bergström G, Lindberg M, Fossum C, Allan GM, Robertsson JA.
Postweaning multisystemic wasting syndrome (PMWS) is causally associated with porcine circovirus type 2 (PCV2) infection of pigs. PCV2 was first demonstrated in Swedish pigs in 1993, although the virus was almost certainly present in pigs in the country...
Published Nov 2007: J Vet Diagn Invest. 2007 Nov;19(6):668-73.
Temporal distribution of porcine circovirus 2 genogroups recovered from postweaning multisystemic wasting syndrome–affected and –nonaffected farms in Ireland and Northern Ireland
Gordon M. Allan, Francis McNeilly, Michael McMenamy, Irene McNair, Steven G. Krakowka, Sirje Timmusk, Dermot Walls, Maria Donnelly, Donal Minahin, John Ellis, Per Wallgren and Caroline Fossum
Porcine circovirus type 2 (PCV2) is now recognized as the essential infectious component of porcine postweaning multisystemic wasting syndrome (PMWS). PMWS was first recognized in high-status, specific pathogen-free pigs in Canada in 1991 and is now an...
Published Nov 2007: Journal of Veterinary Diagnostic Investigation Vol. 19 Issue 6, 591-615
Porcine Circovirus Type 2–associated disease: Update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies
Tanja Opriessnig1 Xiang-Jin Meng and Patrick G. Halbur
Porcine circovirus type 2 (PCV2)–associated disease (PCVAD) continues to be an important differential diagnosis on pig farms in the United States and worldwide. Case trend analyses indicate that the incidence of PCVAD is on the rise in the United States....
Published Sep 2007: Theriogenology. 2007 Oct 1;68(6):896-901. Epub 2007 Aug 27.
Effect of a porcine circovirus type 2 infection on embryos during early pregnancy.
Mateusen B, Maes DG, Van Soom A, Lefebvre D, Nauwynck HJ.
The aim of the present study was to assess the effects of porcine circovirus type 2 (PCV2) on porcine embryos and their receptor sows during the first 21 days of pregnancy. Hatched blastocysts exposed to 10(5.0) TCID(50) PCV2 per ml (strain 1121, fifth...
Published Sep 2007: Acta Vet Hung. 2007 Sep;55(3):389-404.
First description of postweaning multisystemic wasting syndrome (PMWS) in wild boar (Sus scrofa) in Croatia and phylogenetic analysis of partial PCV2 sequences.
Lipej Z, Segalés J, Jemersić L, Olvera A, Roić B, Novosel D, Mihaljević Z, Manojlović L.
This report describes the first case of postweaning multisystemic wasting syndrome (PMWS) in wild boar in Croatia. During the winter season of 2004, eight wild young piglets (of approximately 2 to 5 months of age) were found dead in a fenced hunting area....
Published Sep 2007: Vet Pathol. 2007 Sep;44(5):621-34.
Porcine Circovirus Type 2-Associated Cerebellar Vasculitis in Postweaning Multisystemic Wasting Syndrome (PMWS)-Affected Pigs
F. A. Seeliger, M. l. Brügmann, L. Krüger, I. Greiser-Wilke, J. Verspohl, J. Segalés and W. Baumgärtner
Porcine circovirus type 2 (PCV2) is associated with several syndromes in growing pigs, including postweaning multisystemic wasting syndrome and porcine dermatitis and nephropathy syndrome. In the present study, a previously undescribed neurovascular disorder...
Published Aug 2007: Journal of Veterinary Medicine Series A Volume 54 Issue 6, August 2007
Performance of Fattening Pigs in a Farm Infected with Both Porcine Reproductive and Respiratory Syndrome (PRRS) Virus and Porcine Circovirus Type 2 Following Sow and Piglet Vaccination with an Attenuated PRRS Vaccine
S. K. Kritas, C. Alexopoulos, C. S. Kyriakis, E. Tzika, S. C. Kyriakis
The purpose of the study was to investigate whether, on farms with both post-weaning multisystemic wasting syndrome (PMWS) and porcine reproductive and respiratory syndrome (PRRS), the PRRS vaccination of sows and their fattening pigs protects against...
Published Aug 2007: Australian Veterinary Journal, Volume 85, Number 8, August 2007
Survey of porcine circovirus 2 and postweaning multisystemic wasting syndrome in New South Wales piggeries
Finlaison, D; Kirkland, P; Luong, R; Ross, A
To determine if postweaning multisystemic wasting syndrome (PMWS) is occurring in the New South Wales pig population and to determine the current and past seroprevalence of porcine circovirus 2 (PCV2). Design Pig veterinarians were contacted seeking...









