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PMWS Research Archives
Published Jun 2009: Veterinary Microbiology - Available online 8 June 2009Swine Torque Teno Virus (TTV) Infection and Excretion Dynamics in Conventional Pig Farms
M. Sibila, L. Martinez-Guinó, E. Huerta, A. Llorens, M. Mora, L. Grau-Roma, T. Kekarainen and J. Segalés
Torque teno virus (TTV) is a non-enveloped, single stranded DNA (ssDNA) virus infecting human and non-primate species. Two genogroups of TTV (TTV1 and TTV2) have been described in swine so far. In the present study, TTV1 and TTV2 prevalences in...
Published Jun 2009: Journal of Virology, June 2009, p. 6039-6047, Vol. 83, No. 12
JNK and p38 Mitogen-Activated Protein Kinase Pathways Contribute to Porcine Circovirus Type 2 Infection
Li Wei, Zhongwu Zhu, Jing Wang, and Jue Liu
Infection with a wide variety of viruses often perturbs host cell signaling pathways including the Jun NH2-terminal kinase/stress-activated kinase (JNK/SAPK) and the p38 mitogen-activated protein kinase (p38/MAPK), which are important components of cellular...
Published May 2009: Res Vet Sci. 2009 May 19. [Epub ahead of print]
Distribution of Antibodies Against Porcine Circovirus Type-2 (PCV2) in Single Site and Multi-Site Farrow-to-Finish Farms in Brazil.
Gerber PF, Galinari GC, Silva MX, Campos FS, Reis AC, Lobato ZI.
A comparative serologic study was performed in seven single site (SS) farrow-to-finish farms and four multi-site (MS) farrow-to-finish farms, with or without post-weaning multisystemic wasting syndrome (PMWS). In each farm, 30 blood samples were collected...
Published May 2009: Virology. 2009 Jun 20;389(1-2):91-9. Epub May 6 2009
Porcine Reproductive and Respiratory Syndrome Virus as a Vector: Immunogenicity of Green Fluorescent Protein and Porcine Circovirus Type 2 Capsid Expressed from Dedicated Subgenomic RNAs.
Pei Y, Hodgins DC, Wu J, Welch SK, Calvert JG, Li G, Du Y, Song C, Yoo D.
Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of PRRS, which is characterized by late-term abortions in sows and respiratory disease in young pigs. Using an infectious cDNA clone of North American PRRSV strain P129,...
Published May 2009: The Veterinary Record, May 2009; 164: 599 - 600.
Efficacy of Different Disinfectants In Vitro Against Porcine Circovirus Type 2.
H. B. Kim, K. S. Lyoo, and H. S. Joo
No abstract is available for this article. See 'Journal...
Published Apr 2009: The Veterinary Record, Apr 2009; 164: 519 - 523.
Application of a Protocol for the Diagnosis of Postweaning Multisystemic Wasting Syndrome in Italy
G. Sarli, F. Ostanello, F. Morandi, L. Fusaro, M. Gnudi, B. Bacci, A. Nigrelli, L. Alborali, M. Dottori, F. Vezzoli, G. Barigazzi, L. Fiorentini, V. Sala, G. Leotti, and F. Joisel
Samples of superficial inguinal and bronchial lymph nodes, ileum, tonsil and lung were taken from three to five pigs on each of 61 farms with a clinical history of postweaning multisystemic wasting syndrome (PMWS). The samples were examined histologically...
Published Apr 2009: Veterinary Microbiology - Available online 19 April 2009
Bordetella bronchiseptica aroA Mutant as a Live Vaccine Vehicle for Heterologous Porcine Circovirus Type 2 Major Capsid Protein Expression
Taejung Kim, Nguyen Tat Toan, Jayoung Seo, Bockgie Jung, Jaeil Lee and Bongjoo Lee
Porcine circovirus type 2 (PCV2) infections cause important respiratory diseases in the pig industry and are associated with many bacterial, mycoplasmal, and viral complications. In this study, a heterologous PCV2 major capsid protein (MCP) was expressed...
Published Apr 2009: Arch Virol. 2009;154(5):875-9. Epub Apr 14 2009
Recombination of Two Porcine Circovirus Type 2 strains.
Lefebvre DJ, Van Doorsselaere J, Delputte PL, Nauwynck HJ.
Pigs can be concurrently infected with different PCV2 strains. In this study, a cell-culture-adapted PCV2 strain, originating from a PMWS-affected pig, was purified by limiting dilution. Three different strains were obtained, and one of them was a perfect...
Published Apr 2009: Vet Microbiol. 2009 Apr 10.
Induction of Porcine Post-Weaning Multisystemic Wasting Syndrome (PMWS) in Pigs from PMWS Unaffected Herds Following Mingling with Pigs from PMWS-Affected Herds.
Kristensen CS, Bækbo P, Bille-Hansen V, Bøtner A, Vigre H, Enøøe C, Larsen LE.
In this paper we present the results from two experimental studies (I and II) investigating whether post-weaning multisystemic wasting syndrome (PMWS) can be induced in pigs from PMWS unaffected herds by mingling with pigs from PMWS-affected herds and...
Published Apr 2009: Veterinary Microbiology - Available online 10 April 2009
Development and Evaluation of an Indirect in situ Polymerase Chain Reaction for the Detection of Porcine Circovirus Type 2 in Formalin-Fixed and Paraffin-Embedded Tissue Specimens
Chun-Ming Lin, Chian-Ren Jeng, Shih-Hsuan Hsiao, Chih-Cheng Chang, Chen-Hsuan Liu, Yi-Chieh Tsai, Mi-Yuan Chia and Victor Fei Pang
Taking advantage of the high sensitivity of polymerase chain reaction (PCR) and the cell-localizing ability of in situ hybridization (ISH), an indirect in situ PCR (ISPCR) method was developed for detecting the distribution of porcine circovirus...
Published Mar 2009: J Vet Med Sci. 2009 Mar;71(3):349-53
Genetic Diversity of Porcine Circovirus Type 2 in Korean Pigs with Postweaning Multisystemic Wasting Syndrome During 2005-2007.
Kim HH, Park SI, Hyun BH, Park SJ, Jeong YJ, Shin DJ, Chun YH, Hosmillo M, Lee BJ, Kang MI, Cho KO.
The comparison of nucleotide and deduced amino acid sequence was conducted with 9 porcine circovirus type 2 (PCV2) strains isolated from PCV2-infected pigs with postweaning multisystemic wasting syndrome (PMWS) and 50 tissue samples obtained from PCV2-infected...
Published Mar 2009: Vet Pathol. 2009 Jul;46(4):729-35. Epub Mar 9 2009 .
Ultrastructural findings in Lymph Nodes from Pigs Suffering from Naturally Occurring Postweaning Multisystemic Wasting Syndrome.
Rodriguez-Cariño C, Segalés J.
The aims of this study were to evaluate ultrastructural lesions in lymph nodes from postweaning multisystemic wasting syndrome (PMWS)-affected pigs and to correlate these alterations with detection of viral-like particles (VLPs). Samples of lymph nodes...
Published Mar 2009: Acta Vet Scand. 2009; 51(1): 13. Published online March 27 2009
The Index Herd with PMWS in Sweden: Presence of Serum Amyloid A, Circovirus 2 Viral Load and Antibody Levels in Healthy and PMWS-Affected Pigs
Per Wallgren, Inger Marit Brunborg, Gunilla Blomqvist, Gunnar Bergström, Frida Wikström, Gordon Allan, Caroline Fossum, and Christine Monceyron Jonassen
Background Postweaning Multisystemic Wasting Syndrome (PMWS) is an emerging disease in pigs of multifactorial origin, but associated to porcine circovirus type 2 (PCV2) infection. PMWS was first diagnosed in Sweden at a progeny test station that...
Published Mar 2009: J. Gen. Virol., Mar 2009; 90: 648 - 653
Swine torque teno virus detection in pig commercial vaccines, enzymes for laboratory use and human drugs containing components of porcine origin
Tuija Kekarainen, Laura Martínez-Guinó, and Joaquim Segalés
Torque teno viruses (TTVs) are vertebrate infecting, single-stranded circular DNA viruses. Two genetically distinct TTV genogroups (TTV1 and TTV2) infect swine worldwide with high prevalence. Currently, swine TTVs are considered non-pathogenic, although...
Published Mar 2009: Preventive Veterinary Medicine, Volume 88, Issue 3, 1 March 2009, Pages 213-219
The relationship between porcine circovirus 2 antigen score and antibody titre and histology of lymph nodes in 375 euthanased sick and healthy pigs from 113 British pig farms with and without postweaning multisystemic wasting syndrome.
M.J. Turner, G.F. Medley, K.A. Woodbine, J.A. Slevin, L.E. Green
Data from a cross-sectional study of 113 British pig herds carried out in 2004 were used to investigate the associations between postweaning multisystemic wasting (PMWS) in pigs and herds and porcine circovirus 2 (PCV2) antigen score and antibody titre,...
