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PMWS Research Archives
Published Nov 2011: Virus Res. 2011 Nov 11. [Epub ahead of print]Cell Tropism and Entry of Porcine Circovirus 2.
Nauwynck HJ, Sanchez R, Meerts P, Lefebvre DJ, Saha D, Huang L, Misinzo G.
Porcine circovirus 2 (PCV2) may induce reproductive failure (return to oestrus, embryonic death, mummification, weak- and stillborn piglets) and postweaning multisystemic wasting syndrome (PMWS). Furthermore, it may modulate the immunity in such a way...
Published Nov 2011: Virol J. 2011 Nov 2;8(1):497. [Epub ahead of print]
Loop-Mediated Isothermal Amplification for Detection of Porcine Circovirus Type 2.
Zhou S, Han S, Shi J, Wu J, Yuan X, Cong X, Xu S, Wu X, Li J, Wang J.
BACKGROUND: Porcine circovirus type 2 (PCV2) is the primary causative agent of the emerging swine disease known as postweaning multisystemic wasting syndrome (PMWS). Nowadays, polymerase chain reaction (PCR) is still the most widespread technique...
Published Nov 2011: J. Virol. November 2011; published ahead of print 24 August 2011
Coreplication of the Major Genotype Group Members of Porcine Circovirus Type 2 as a Prerequisite to Coevolution May Explain the Variable Disease Manifestations
Siegfried Khaiseb, Titus Sydler, Dieter Zimmermann, Andreas Pospischil, Xaver Sidler, and Enrico Brugnera
A member of the family Circoviridae, porcine circovirus type 2 (PCV2), is associated with postweaning multisystemic wasting syndrome (PMWS), a recent emerging disease worldwide. PCV2 is also found in clinically asymptomatic animals. This paradoxical finding...
Published Oct 2011: Virus Res. 2011 Oct 20. [Epub ahead of print]
Porcine Circovirus Type 2 and its Associated Diseases in Korea.
Chae C.
This review describes the characterization of porcine circovirus type 2 (PCV2), the field situation of porcine circovirus-associated disease (PCVAD) and the PCV2 vaccine in Korea. PCVAD has been considered the most devastating disease in Korean livestock...
Published Oct 2011: Virus Res. 2011 Oct 15. [Epub ahead of print]
Porcine Circovirus Type 2 and its Associated Diseases in China.
Ge X, Wang F, Guo X, Yang H.
Porcine circovirus type 2 (PCV2) has been recognized as an important vial pathogen for global swine industry. The virus is associated with postweaning multisystemic wasting syndrome (PMWS) and other syndrome diseases collectively known as porcine circovirus-associated...
Published Oct 2011: Arch Virol. 2011 Oct 2. [Epub ahead of print]
Genetic Characterization and Phylogenetic Analysis of Porcine Circovirus Type 2 (PCV2) in Serbia.
Savic B, Milicevic V, Jakic-Dimic D, Bojkovski J, Prodanovic R, Kureljusic B, Potkonjak A, Savic B.
Porcine circovirus type 2 (PCV2) is the main causative agent of postweaning multisystemic wasting syndrome (PMWS). To characterize and determine the genetic diversity of PCV2 in the porcine population of Serbia, nucleotide and deduced amino acid sequences...
Published Sep 2011: Veterinary Record 2011; Volume 169, Issue 13 September
Severity of PMWS: Investigating Risk Factors on Farms
P. Alarcon, M. Velasova, A. Mastin, A. Nevel, K. D. C. Stärk, B. Wieland
This study identified risk factors associated with different levels of severity of postweaning multisystemic wasting syndrome (PMWS) on pig farms in England. During 2008/09, 147 farms across England were studied. They were recruited through a porcine...
Published Sep 2011: Veterinary Microbiology - Volume 152, Issues 3-4, 28 September 2011, Pages 235-246
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Influences Infection Dynamics of Porcine Circovirus Type 2 (PCV2) Subtypes PCV2a and PCV2b by Prolonging PCV2 Viremia and Shedding
A. Sinha, H.G. Shen, S. Schalk, N.M. Beach, Y.W. Huang, X.J. Meng, P.G. Halbur, T. Opriessnig
The objective of this study was to determine the effect of porcine reproductive and respiratory syndrome virus (PRRSV) infection on porcine circovirus type 2 (PCV2) subtypes a (PCV2a) or b (PCV2b) viremia and shedding characteristics in oral, nasal and...
Published Sep 2011: Vaccine - Available online 21 September 2011
Construction and Immunogenicity of Recombinant Adenovirus Expressing ORF2 of PCV2 and Porcine IFN Gamma
Liu Genmei, Luo Manlin, Chen Ruiai, Huang Hongliang, Pei Dangshuai
The capsid structural protein encoded by the gene ORF2 of Porcine Circovirus Type 2 is critical for eliciting the broad protective immunity. We constructed and characterized the recombinant adenovirus encoding the capsid and porcine IFN gamma, designated...
Published Sep 2011: Virus Research - Available online 16 September 2011.
Discovery and Evolving History of Two Genetically Related but Phenotypically Different Viruses, Porcine Circoviruses 1 and 2
Gordon Allana, Steven Krakowka, John Ellis, Catherine Charreyre
Porcine circoviruses (PCVs) belong to the genus Circovirus, family Circoviridae, and are the smallest non-enveloped, single stranded, negative sense, circular DNA viruses that replicate autonomously in mammalian cells. Two types of PCV have...
Published Sep 2011: Virus Research - Available online 16 September 2011.
Concurrent Infections are Important for Expression of Porcine Circovirus Associated Disease
Tanja Opriessnig, Patrick G. Halbur
Porcine circovirus type 2 (PCV2) is the essential component of porcine circovirus disease (PCVD) as the disease syndrome is referred to in Europe and porcine circovirus associated disease (PCVAD) as it is referred to in North America. Singular PCV2 infection...
Published Sep 2011: Virology Journal 2011, 8:437
Genetic Characterization of Porcine Circovirus 2 found in Malaysia
Seetha Jaganathan, Ooi P Toung, Phang L Yee, Tan D Yew, Choo P Yoon and Lim B Keong
Background Porcine circovirus type 2 is the primary etiological agent associated with a group of complex multi-factorial diseases classified as Porcine Circovirus Associated Diseases (PCVAD). Sporadic cases reported in Malaysia in 2007 caused...
Published Sep 2011: Infection, Genetics and Evolution - Available online 7 September 2011.
Molecular Study of Porcine Circovirus Type 2 Circulating in Portugal
Ana M. Henriques, Margarida Duarte, Teresa Fagulha, Fernanda Ramos, SÃlvia C. Barros, Tiago LuÃs, Miguel Fevereiro
Porcine circovirus type 2 (PCV2) belongs to the genus Circovirus of the Circoviridae family and has been associated with a disease named postweaning multisystemic wasting syndrome (PMWS). In Portugal the disease caused severe problems mainly...
Published Sep 2011: Virology - Volume 419, Issue 2, 25 October 2011, Pages 57-63
Porcine Circovirus Genotype 2a (PCV2a) and Genotype 2b (PCV2b) Recombinant Mutants showed Significantly Enhanced Viral Replication and Altered Antigenicity in vitro
Longjun Guo, Yuehua Lu, Yanwu Wei, Liping Huang, Hongli Wu, Changming Liu
Two recombinant mutants of porcine circovirus type 2 (PCV2), which resulted from replacement of a genomic fragment containing the open reading frame 2 (ORF2) of genotype PCV2b with that of genotype PCV2a, were obtained initially from co-infection with...
Published Sep 2011: Veterinary Record 2011 - Published Online 2 September 2011
Linked Outbreaks and Control of Porcine Reproductive and Respiratory Syndrome and Postweaning Multisystemic Wasting Syndrome in a Pig Farm in Poland
T. Stadejek, K. Podgorska, M. Porowski, A. Jablonski and Z. Pejsak
In a newly established farrow-to-finish farm (porcine reproductive and respiratory virus [PRRSV]-free, porcine circovirus type 2 [PCV-2]-infected), reproductive failure was seen seven months after population. The conception rate dropped from 89 to 51...
