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PMWS Research Archives
Published Aug 2011: BMC Microbiology 2011, 11:188 - AugustIdentification of One Critical Amino Acid That Determines a Conformational Neutralizing Epitope in the Capsid Protein of Porcine Circovirus Type 2
Li P Huang, Yue H Lu, Yan W Wei, Long J Guo and Chang M Liu
Background Porcine circovirus type 2 (PCV2) is associated with post-weaning multisystemic wasting syndrome (PMWS) in pigs. Currently, there is considerable interest in the immunology of PCV2; in particular, the immunological properties of the...
Published Aug 2011: Preventive Veterinary Medicine Volume 101, Issues 1-2, 1 August 2011, Pages 79-88
Diagnostic Performance Measures of ELISA and Quantitative PCR Tests for Porcine Circovirus Type 2 Exposure using Bayesian Latent Class Analysis
Charles Haley, Bruce Wagner, Sumathy Puvanendiran, Juan Abrahante, Michael P. Murtaugh
Porcine circovirus 2 (PCV2) is believed to be a necessary but not sufficient underlying cause of porcine circovirus associated disease (PCVAD) in swine (Opriessnig et al., 2007). Since the potential threat of PCVAD is dependent on the prevalence of PCV2...
Published Aug 2011: Research in Veterinary Science - Available online 27 August 2011.
Detection of Circoviruses and Porcine Adenoviruses in Water Samples Collected from Swine Manure Treatment Systems
A. Viancelli, L.A.T. Garcia, A. Kunzb, R. Steinmetz, P.A. Esteves, C.R.M. Barardi
Samples collected from two swine manure treatment systems including: swine manure treatment system and demonstrative unit (SMTS and DU), were analyzed by qPCR to quantify the amount of porcine adenovirus (PAdV) and porcine circovirus (PCV2) present. Positive...
Published Aug 2011: Journal of Comparative Pathology - Volume 145, Issues 2-3, August-October 2011, Pages 261-270
Experimental Reproduction of Porcine Circovirus Type 2 (PCV2)-Associated Enteritis in Pigs Infected with PCV2 Alone or Concurrently with Lawsonia intracellularis or Salmonella typhimurium
T. Opriessnig, D.M. Madson, M. Roof, S.M. Layton, S. Ramamoorthy, X.J. Meng, P.G. Halbur
Porcine circovirus (PCV)-associated disease (PCVAD) has emerged to become one of the most economically important pig diseases globally. One of the less commonly recognized clinical manifestations of PCVAD is PCV2 type 2 (PCV2)-associated enteritis in...
Published Aug 2011: Vaccine - Available online 9 August 2011.
Investigations of Porcine Circovirus Type 1 (PCV1) in Vaccine-Related and Other Cell Lines
Hailun Ma, Syed Shaheduzzaman, Dhanya K. Willliams, Yamei Gao, Arifa S. Khan
Porcine circovirus type 1 (PCV1) is highly prevalent in swine and was recently reported in U.S. licensed rotavirus vaccines. Since animal-derived raw materials, such as cells, trypsin, and serum, can be a major source of introducing virus contamination...
Published Aug 2011: Vet Microbiol. Volume 151, Issues 3-4, 5 August 2011, Pages 245-254
Phylogenetic Networks to Study the Origin and Evolution of Porcine Circovirus Type 2 (PCV2) in Cuba.
Pérez LJ, de Arce HD, Cortey M, DomÃnguez P, Percedo MI, Perera CL, Tarradas J, FrÃas MT, Segalés J, Ganges L, Núñez JI.
Porcine circovirus type 2 (PCV2) is the essential etiological infectious agent of postweaning multisystemic wasting syndrome (PMWS), which is considered one of the most economically important swine diseases worldwide. In this study, a comparison between...
Published Aug 2011: The Journal of Virology, August 2011,p. 7856-7862, Vol. 85, No. 15
The 2.3-Angstrom Structure of Porcine Circovirus 2
Reza Khayat, Nicholas Brunn, Jeffrey A. Speir, John M. Hardham, Robert G. Ankenbauer, Anette Schneemann, and John E. Johnson
Porcine circovirus 2 (PCV2) is a T=1 nonenveloped icosahedral virus that has had severe impact on the swine industry. Here we report the crystal structure of an N-terminally truncated PCV2 virus-like particle at 2.3-Ã… resolution, and the cryo-electron...
Published Jul 2011: Theriogenology Volume 76, Issue 2, 15 July 2011, Pages 351-360
Porcine Circovirus Type 2 (PCV2) Vaccination is Effective in Reducing Disease and PCV2 Shedding in Semen of Boars Concurrently Infected with PCV2 and Mycoplasma hyopneumoniae
T. Opriessnig, D.M. Madson, S. Schalk, S. Brockmeier, H.G. Shen, N.M. Beach, X.J. Meng, R.B. Baker, E.L. Zanella, P.G. Halbur
The objectives were to determine whether the amount of porcine circovirus type 2 (PCV2) shed in semen increased in boars experimentally coinfected with Mycoplasma hyopneumoniae (MHYO), and whether PCV2 vaccination of boars prior to PCV2 exposure reduced...
Published Jul 2011: The Veterinary Journal Volume 189, Issue 1, July 2011, Pages 58-62
Comparative Efficacy of Three Commercial PCV2 Vaccines in Conventionally Reared Pigs
KwangSoo Lyoo, HanSoo Joo, Brian Caldwell, HyeunBum Kim, Peter R. Davies, Jerry Torrison
The aim of this study was to compare the efficacy of three commercial porcine circovirus type 2 (PCV2) vaccines. Twenty 3-week old pigs were injected with one of three different vaccines, A, B, C, or were unvaccinated controls. Pigs in group A were...
Published Jul 2011: Prev Vet Med. 2011 Sep 1;101(3-4):182-91. Epub 2011 Jul 13.
Farm Level Risk Factors Associated With Severity of Post-Weaning Multi-Systemic Wasting Syndrome.
Alarcon P, Velasova M, Mastin A, Nevel A, Stärk KD, Wieland B.
A cross-sectional study involving 147 pig farms across England was conducted in 2008-2009. Farm severity of post-weaning multi-systemic wasting syndrome (PMWS) was estimated through the use of an algorithm that combined data on post-weaning mortality,...
Published Jul 2011: Virology Journal 2011, 8:341
Functional Exchangeability of the Nuclear Localization Signal (NLS) of Capsid Protein between PCV1 and PCV2 In Vitro: Implications for the Role of NLS In Viral Replication
Jiangbing Shuai, Linglin Fu, Xiaofeng Zhang, Binglin Zhu, XiaoLiang Li, Yongqiang He and Weihuan Fang
Abstract (provisional) Background Porcine circovirus type 2 (PCV2) is believed to be the primary causative agent of postweaning multisystemic wasting syndrome (PMWS). It is supposed that capsid protein of PCV may contribute to replication control...
Published Jun 2011: Animal Reproduction Science Volume 126, Issues 1-2, June 2011, Pages 108-114
Removal of Virus from Boar Semen Spiked with Porcine Circovirus Type 2
Gunilla Blomqvist, Maria Persson, Margareta Wallgren, Per Wallgren, Jane M. Morrell
The virus porcine circovirus type 2 (PCV2) is associated with different disease entities, including reproductive failure. The objective of this study was to investigate the use of a semen processing technique for the elimination of infectious PCV2 in...
Published Jun 2011: Virus Research Volume 158, Issues 1-2, June 2011, Pages 281-288
Natural Recombinants Derived from Different Patterns of Recombination Between two PCV2b Parental Strains
Lin Cai, Xue Han, Jianqiang Ni, Xiuling Yu, Zhi Zhou, Xinyan Zhai, Xizhao Chen, Kegong Tian
Porcine circovirus diseases (PCVD) are globally emerging diseases that have huge economic impacts on swine industry. Porcine circovirus type 2 (PCV2) is considered to be the essential primary causative agent of PCVD. In the present study, recombination...
Published Jun 2011: Veterinary Microbiology
Microarray and Cytokine Analyses of Field Cases of Pigs with Diarrhoea
M. Jacobsona, M. Andersson, R. Lindberg, C. Fossum and M. Jensen-Waern
This field study explored the cytokine expression in intestinal tissue and serum from 19 diarrhoeic and 9 healthy pigs in herds with a long-time history of Lawsonia intracellularis-infection. The disease, proliferative enteropathy (PE), is associated...
Published Jun 2011: Research in Veterinary Science - Available online 12 June 2011.
Fatal Bronchopneumonia in a Metastrongylus Elongatus and Porcine Circovirus Type 2 Co-Infected Pig
G. Marruchella, B. Paoletti, R. Speranza, G. Di Guardo
Porcine circovirus type 2 (PCV2) infection is distributed worldwide and PCV2-associated disease (PCVAD) is considered among the most economically relevant ones to the global swine industry. PCV2 is known to play a causal role in the porcine respiratory...
