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PMWS Research Archives
Published Mar 2007: Journal of Comparative PathologyVaccination of Porcine Circovirus type 2 (PCV2)-infected Sows against Porcine Parvovirus (PPV) and Erysipelas: Effect on Post-weaning Multisystemic Wasting Syndrome (PMWS) and on PCV2 Genome Load in the Offspring
N. Rose, P. Blanchard, R. Cariolet, B. Grasland, N. Amenna, A. Oger, B. Durand, M. Balasch, A. Jestin and F. Madec
The effect of different Parvovirus+Erysipelas vaccination schemes in PCV2-infected sows on PMWS outcome in the offspring was investigated under experimental conditions. Six PCV2-free sows were first infected oro-nasally with PCV2 two months before insemination...
Published Mar 2007: J Vet Diagn Invest. 2007 Mar;19(2):135-41.
A novel method for the detection of porcine circovirus type 2 replicative double stranded viral DNA and nonreplicative single stranded viral DNA in tissue sections.
Hamberg A, Ringler S, Krakowka S.
Porcine circovirus type 2 (PCV2), an economically important pathogen of swine, is the necessary cause of post weaning multisystemic wasting disease (PMWS); PCV2 infection is associated with porcine dermatitis and nephritis syndrome (PDNS). Current immunohistochemical...
Published Mar 2007: Acta Vet Hung. 2007 Mar;55(1):151-6.
Porcine circovirus type 2 and associated diseases in Romania--short communication.
Cadar D, Cságola A, Dán A, Deim Z, Spînu M, Miclăuş V, Köbölkuti L, Czirják G, Tuboly T.
Porcine circovirus type 2 (PCV2) has been demonstrated to be the causal agent for postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS). This report describes the first detection of PCV2 and associated...
Published Mar 2007: J Zhejiang Univ Sci B. 2007 Mar;8(3):162-9.
Detection of PCV2 DNA by SYBR Green I-based quantitative PCR.
Yang ZZ, Habib M, Shuai JB, Fang WH.
We developed an assay for the detection and quantitation of porcine circovirus type 2 (PCV2) with the SYBR Green I-based real-time PCR. The real-time PCR provides a broad dynamic range, detecting from 10(3) to 10(11) copies of DNA per reaction. No cross-reactions...
Published Jan 2007: Virology - Volume 357, Issue 2 , 20 January 2007, Pages 175-185
Molecular evolution of porcine circovirus type 2 genomes: Phylogeny and clonality
A. Olvera, M. Cortey and J. Segalés
Porcine circoviruses (PCVs) type 1 (PCV1) and type 2 (PCV2) show high levels of nucleotide similarity, but PCV1 is considered non-pathogenic and PCV2 has been associated with several disease outcomes in pigs, mainly postweaning multisystemic wasting syndrome...
Published Jan 2007: J Vet Diagn Invest. 2007 Jan;19(1):109-112
Brain lesions in pigs affected with postweaning multisystemic wasting syndrome.
Corręa AM, Zlotowski P, de Barcellos DE, da Cruz CE, Driemeier D.
Anti-porcine circovirus type 2 (anti-PCV2) immunostaining was associated with cerebellar lymphohistiocytic vasculitis combined with hemorrhages (50 pigs) or with lymphohistiocytic meningitis (23 pigs) in pigs naturally affected with postweaning multisystemic...
Published Jan 2007: J Vet Diagn Invest. 2007 Jan;19(1):60-8
Epidemiological investigation of the prevalence and features of postweaning multisystemic wasting syndrome in Japan.
Kawashima K, Katsuda K, Tsunemitsu H.
To investigate the prevalence and features of postweaning multisystemic wasting syndrome (PMWS) in Japan, an epidemiological study was conducted in 692 weaned pigs with various clinical signs, commonly including wasting or weight loss, collected from...
Published Jan 2007: Veterinary Microbiology - Volume 119, Issues 2-4 , 31 January 2007, Pages 97-104
Generation and immunogenicity of a recombinant pseudorabies virus expressing cap protein of porcine circovirus type 2
Yunfeng Songa, Meilin Jina, Songlin Zhang, Xiaojuan Xu, Shaobo Xiao, Shengbo Cao and Huanchun Chena
Porcine circovirus type 2 (PCV2) is associated with post-weaning multisystemic wasting syndrome (PMWS), which is an important economical disease affecting the pig industry worldwide. In order to develop an effective vaccine for PMWS, a recombinant pseudorabies...
Published Dec 2006: Australian Veterinary Journal, Volume 84, Number 12, December 2006, pp. 421-425(5)
Genetic characterisation of Australian strains of porcine circovirus types 1 and 2
Muhling, J; Raye, WS; Buddle, JR; Wilcox, GE
Objective As post-weaning multi-systemic wasting syndrome (PMWS) has not been identified within Australia, to determine if the absence of disease was associated with genetic differences between the strains of porcine circovirus (PCV) present in...
Published Dec 2006: Vet Microbiol. 2006 Dec 9; [Epub ahead of print]
Protection of pigs against post-weaning multisystemic wasting syndrome by a recombinant adenovirus expressing the capsid protein of porcine circovirus type 2.
Wang X, Jiang P, Li Y, Jiang W, Dong X.
Post-weaning multisystemic wating syndrome (PMWS) associated with PCV2 was one of the most costly diseases currently faced by the swine industry. In order to develop a vaccine to control this disease, we previously constructed a recombinant adenovirus...
Published Dec 2006: Vet Rec. 2006 Dec 2;159(23):761-8.
Survey of pigs' kidneys with lesions consistent with PMWS and PDNS and ochratoxicosis. Part 2: pathological and histological findings.
Gresham A, Done S, Livesey C, Macdonald S, Chan D, Sayers R, Clark C, Kemp P.
One thousand condemned pigs' kidneys were collected in February 2002 from two pig abattoirs in England to assess the lesions due to postweaning multisystemic wasting syndrome (pmws) and porcine dermatitis and nephropathy syndrome (pdns) and the possible...
Published Dec 2006: Dev Biol (Basel). 2006;126:107-13; discussion 325-6.
Swine and circovirus.
Banks M, Grierson S, Tucker D, Bailey M, Donadeau M, Sargent C, King D, Mellencamp M.
In the 1990s Post-weaning, multi-systemic wasting syndrome (PMWS) emerged in N. America and Europe as a major disease problem with significant welfare and economic consequences for pig producers. The disease, characterised by wasting, respiratory, enteric...
Published Dec 2006: J Swine Health Prod 2006;14(3):133-139
Effects of adjuvants on porcine circovirus type 2-associated lesions
Marlin J. Hoogland, DVM, MS; Tanja Opriessnig, Dr med vet; Patrick G. Halbur, DVM, PhD
Objective: To determine if adjuvants differ in their ability to trigger lesions associated with porcine circovirus type 2 (PCV2). Methods: Ninety pigs randomly assigned to five groups were vaccinated intramuscularly at 4 and 6 weeks...
Published Nov 2006: Vet Rec. 2006 Nov 25;159(22):737-42
Survey of pigs' kidneys with lesions consistent with PMWS and PDNS and ochratoxicosis. Part 1: concentrations and prevalence of ochratoxin A.
Gresham A, Done S, Livesey C, Macdonald S, Chan D, Sayers R, Clark C, Kemp P.
One thousand condemned pigs' kidneys were collected in February 2002 from two pig abattoirs in England to assess the possible contribution of ochratoxicosis to postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome...
Published Nov 2006: Vet Pathol. 2006 Nov;43(6):993-7
Immunohistochemical MHC-II and interleukin 2-R (CD25) expression in lymph nodes of pigs with spontaneous postweaning multisystemic wasting syndrome (PMWS).
Mandrioli L, Sarli G, Zengarini M, Panarese S, Marcato PS.
Immunohistochemical expression of immunocompetent cells bearing major histocompatibility complex (MHC-II) and interleukin 2-R (IL2-R) (CD25) molecules was performed on lymph nodes with spontaneous postweaning multisystemic wasting syndrome (PMWS). Control...
