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PMWS Research Archives
Published Jul 2006: Can J Vet Res. 70(3):161-7Postweaning mortality in Manitoba swine.
Dewey CE, Johnston WT, Gould L, Whiting TL.
A case-control study to investigate the contribution of postweaning multisystemic wasting syndrome (PMWS) and Porcine circovirus type 2 (PCV-2) to deaths among piglets of nursery age (19 to 68 d) in Manitoba indicated a significant positive association...
Published Jul 2006: Veterinary Microbiology, Volume 115, Issue 4, 20 July 2006, Pages 311-319
Bacterial lipopolysaccharide induces porcine circovirus type 2 replication in swine alveolar macrophages
Hui-Wen Chang, Victor Fei Pang, Liang-Jiun Chen, Mi-Yuan Chia, Yi-Chieh Tsai and Chian-Ren Jeng
Monocyte/macrophage lineage cells are major target cells of porcine circovirus type 2 (PCV2). From tissues of field pigs suffering from postweaning multisystemic wasting syndrome (PMWS), both intracytoplasmic and intranuclear PCV2 signals, including antigens...
Published Jul 2006: Can J Vet Res. 2006 Jul;70(3):161-7
Postweaning mortality in Manitoba swine.
Dewey CE, Johnston WT, Gould L, Whiting TL.
A case-control study to investigate the contribution of postweaning multisystemic wasting syndrome (PMWS) and Porcine circovirus type 2 (PCV-2) to deaths among piglets of nursery age (19 to 68 d) in Manitoba indicated a significant positive association...
Published May 2006: Journal of Virology, p. 5065-5073, Vol. 80, No. 10
The ORF3 Protein of Porcine Circovirus Type 2 Is Involved in Viral Pathogenesis In Vivo
Jue Liu, Isabelle Chen, Qingyun Du, Huikheng Chua, and Jimmy Kwang
Porcine circovirus type 2 (PCV2) is the primary causative agent of an emerging swine disease, postweaning multisystemic wasting syndrome. We previously showed that a novel identified protein, ORF3, was not essential for PCV2 replication in cultured PK15...
Published May 2006: Tijdschr Diergeneeskd. ;131(9):318-25.
Risk factors for clinical signs of PMWS and PDNS in pigs in The Netherlands: a case-control study
Elbers AR, de Jong MF, Wellenberg GJ.
Potential risk factors for clinical signs of post-weaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS) in pigs in the Netherlands were investigated in a matched case-control study using a questionnaire (personal...
Published May 2006: Pig Journal Volume: 57, Proceedings Section
Where are we now? Post-Weaning Multisystemic Wasting Syndrome (PMWS) in Great Britain, May 2005
L.E. Green, K.A. Woodbine, M.J. Turner, J. Slevin, A.L. Kilbride, E.J. Novell, C. Schnier, M. Keeling and G.F. Medley
This paper sets out the results of an analysis made by the authors to date. They assert that there is more work to be done and that such work may affect current understanding of Post-weaning multisystemic wasting syndrome (PMWS) and may refute some of...
Published May 2006: Pig Journal Volume: 57, Proceedings Section
Risk Factors for Herd Breakdown with Post-Weaning Multisystemic Wasting Syndrome (PMWS) in Great Britain
K.A. Woodbine, G.F. Medley, J. Slevin, A.L.Kilbride, E.J. Novell, M.J. Turner, M.J. Keeling and L.E. Green
A retrospective cohort study of 116 British pig farms was undertaken to investigate the epidemiological risk factors for Post-weaning Multisystemic Wasting Syndrome (PMWS) in Great Britain (GB). Analysis of the spread of PMWS showed that PMWS occurred...
Published May 2006: Pig Journal Volume: 57, Refereed Section
Post-Weaning Multisystemic Wasting Syndrome: Studies on Disease Progression in Relation to Serum Antibody Levels to Porcine Circovirus Type 2 (PCV2) in Sows and Piglets and PCV2 Viraemia in Young Pigs
F. McNeilly, I. McNair, G. Stewart, G. Allan, L.E. Green, C. Waldner, J. Ellis, D. Armstrong and S. Krakowka
Blood samples were taken from 78 sows and 774 piglets on five farrow-to-finish farms in England. Three of these farms had ongoing outbreaks of Post-weaning Multisystemic Wasting Syndrome (PMWS) and two were unaffected up to, and during, the time of the...
Published May 2006: The Veterinary Journal Volume 171, Issue 3, Pages 566-569.
Muco-cutaneous candidiasis in two pigs with postweaning multisystemic wasting syndrome
Priscila Zlotowski, Daniela B. Rozza, Caroline A. Pescador, David E. Barcellos, Laerte Ferreiro, Edna M.C. Sanches and David Driemeier
In two distinct commercial swine herds, poor weight gain and an increased number of animals showing wasting were observed among nursery and growing pigs. Cases of postweaning multisystemic wasting syndrome (PMWS) and infection with Haemophilus parasuis...
Published May 2006: The Veterinary Journal Volume 171, Issue 3, Pages 570-573
Detection of porcine circovirus type 1 in commercial pig vaccines using polymerase chain reaction
Josefina Quintana, Joaquim Segalés, Maria Calsamiglia and Mariano Domingo
The absence of extraneous viruses is a requirement in the quality control of vaccines for veterinary use in the European Pharmacopoeia. A polymerase chain reaction (PCR) assay for the detection of porcine circovirus type 1 (PCV1) and type 2 (PCV2) was...
Published May 2006: Vet Pathol. 43(3):281-93.
Evidence of Breed-dependent Differences in Susceptibility to Porcine Circovirus Type-2-associated Disease and Lesions.
Opriessnig T, Fenaux M, Thomas P, Hoogland MJ, Rothschild MF, Meng XJ, Halbur PG.
Porcine circovirus type 2 (PCV2) has been confirmed as the primary cause of postweaning multisystemic wasting syndrome (PMWS). However, in the field, PMWS is seen only in a small percentage of pigs infected with PCV2. The overall objective of the study...
Published May 2006: The Veterinary Journal Volume 171, Issue 3, Pages 396-397.
The effects of transplacental porcine circovirus type 2 infection on porcine epidemic diarrhoea virus-induced enteritis in preweaning piglets
K. Jung, J. Kim, Y. Ha, C. Choi and C. Chae
The effects of transplacental porcine circovirus type 2 (PCV2) infection on porcine epidemic diarrhoea virus (PEDV)-induced enteritis were examined in neonatal piglets. Six pregnant sows were randomly allocated to an infected (n = 3) or control group...
Published Apr 2006: J Vet Med Sci.68(4):387-91
Occurrence of swine salmonellosis in postweaning multisystemic wasting syndrome (PMWS) affected pigs concurrently infected with porcine reproduction and respiratory syndrome virus (PRRSV).
Murakami S, Ogawa A, Kinoshita T, Matsumoto A, Ito N, Nakane T.
Fourteen diseased pigs from four farms in which there had been an outbreak of salmonellosis were investigated. Granulomatous inflammation with depletion of lymphocytes was observed in the swollen lymph nodes in these pigs. Antigens to porcine circovirus...
Published Apr 2006: Vaccine. 12;24(16):3374-80. Epub 2006 Feb 23.
Construction and immunogenicity of recombinant adenovirus expressing the capsid protein of porcine circovirus 2 (PCV2) in mice.
Wang X, Jiang W, Jiang P, Li Y, Feng Z, Xu J.
Porcine circovirus 2 (PCV2) has been implicated as the etiological agent of some diseases, mainly postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS). The capsid (Cap) protein encoded by the PCV2 ORF2...
Published Apr 2006: Journal of Virology, p. 3487-3494, Vol. 80, No. 7.
Porcine Circovirus 2 Uses Heparan Sulfate and Chondroitin Sulfate B Glycosaminoglycans as Receptors for Its Attachment to Host Cells
Gerald Misinzo, Peter L. Delputte, Peter Meerts, David J. Lefebvre, and Hans J. Nauwynck
Monocyte/macrophage lineage cells are target cells in vivo for porcine circovirus 2 (PCV2) replication. The porcine monocytic cell line 3D4/31 supports PCV2 replication in vitro, and attachment and internalization kinetics of PCV2 have been established...
