New Weapon In The Fight Against PRRSV

MINNESOTA - A Minnesota-based company has announced the launch of a new technology for producing PRRSV vaccine, which offers greater antigen content as well as the option for including multiple strains.
calendar icon 16 June 2006
clock icon 3 minute read
MJ Biologics

MJ Biologics, based in Mankato, MN has launched SelectigenTM MJPRRSTM Technology (patent pending) for producing PRRS Viral Antigen Concentrate Subunit Vaccine. The autogenous (custom) killed vaccine is produced using the SelectigenTM MJPRRSTM Technology. This technology was originally invented by Dr. HanSoo Joo, professor at the University of Minnesota, College of Veterinary Medicine and exclusively licensed from the University of Minnesota.

This process focuses on selectively harvesting and concentrating viral antigens from PRRS-infected tissue culture prior to assembling an intact virus. Under this new technology, cells are harvested at a point in time to achieve the optimum degree of incubation, harvesting, and inactivation prior to the release of mature virus with intact envelopes. The individual viral antigen components are then concentrated in a free form. The vaccine produced through this Selectigen™ MJPRRSTM process is able to maximize the viral antigen content in the product.

In field trials, autogenous vaccine formulated using this method offered cross protection against several different strains of the PRRS virus. Several experimental studies pursued by independent veterinarians demonstrated protection against heterologous PRRS virus challenges. For instance, in trials including unvaccinated naïve gilts and vaccinated sows from a 5000-sow farm, the study proved much better cross-protection than has been shown with other PRRS-control strategies. In these trials, the challenge viruses used were strains unrelated with those in the vaccine, and were also different from any strains to which the sows in the test herd had been exposed.

MJ Biologics has sublicensed the SelectigenTM MJPRRSTM Technology to Newport Laboratories, Worthington, MN, to market and distribute autogenous biologics. Newport is currently accepting orders for custom products made from PRRS virus collected from affected swine herds.

For more information on the SelectigenTM MJPRRSTM Technology, as well as subsequent autogeneous biologics, contact MJ Biologics at (507) 385-0299, or at or Newport Laboratories at (800) 220-2522 or at

M. Wagner and B.D. Roggow, Fairmont Veterinary Clinic, Fairmont, MN,
H.S. Joo, College of Veterinary Medicine, University of Minnesota, St. Paul, MN

Further Information

To read more about PRRS, click here

Source: MJ Biologics - 15th June 2006

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