Probiotic Treatment Reduces Salmonella Infection In Pigs

UK - Researchers from Ireland found that treatment with probiotic bacteria reduced Salmonella infection in pigs and may have potential human applications. They report their findings in the March 2007 issue of the journal Applied and Environmental Microbiology.
calendar icon 20 March 2007
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Salmonella spp. is one of the major causes of food-borne gastroenteritis worldwide, with an estimated 160,000 cases reported annually in the European Union alone. Probiotics, described as live microorganisms believed to promote a health benefit in the host when administered in controlled amounts, have emerged in recent years as an alternative method to counteract bacterial infections. Previous studies have focused largely on the lactic acid bacteria (LAB) group and many have shown beneficial effects in small animal models challenged with gastrointestinal infection.

In the study pigs were divided into two groups, one of which received milk containing five LAB probiotic strains and the other, serving as a control group, received regular milk for 30 days. Following 6 days of treatment the pigs were then challenged orally with Samonella enterica serovar Typhimurium after which their health and feces were monitored for 23 days. The pigs receiving probiotic treatment showed reduced incidence, severity, and duration of diarrhea as well as significantly lower numbers of Salmonella in fecal samples 15 days postinfection.

Source: Science Daily
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