Spray-dried Porcine Plasma: a Safe Feed Ingredient, Says Association

US - North American Spray Dried Blood and Plasma Products association, NASDBPP concludes from its experiments that current methods of processing spray-dried porcine plasma inactivate the porcine epidemic diarrhoea (PED) virus and make it a safe feed ingredient.

19 June 2014

3 minute read

By: Jackie Linden

North America

According to a report released by the North American Spray Dried Blood and Plasma Products association, NASDBPP and FDA conducted controlled experiments to test the hypothesis that spray-dried porcine plasma may contain infective PED virus (PEDv), reports the American Association of Swine Veterinarians (AASV).

NASDBPP concludes: “The results of these experiments support the conclusion that spray-dried porcine plasma is a safe feed ingredient. The manufacturing process under industry standards inactivates PEDv. However, like any feed ingredient, post-processing contamination is a constant risk and may be the cause of the infective PEDv found on porcine plasma as reported by the CFIA.”

**Hypothesis: If PCR+ spray-dried porcine plasma contains infective PEDv and is a vector spreading PED**
Then:	Results of controlled experiments:
1: PEDv will survive spray drying.	1: Spray drying inactivated PEDv.
2: Retained samples of plasma investigated by CFIA in bioassay will contain infective PEDv.	2: Retained plasma samples subjected to bioassay studies by FDA and NASDBPP were not infective for PEDv.
3: Nursery feed containing PEDv PCR+ plasma should infect pigs.	3: Two independent studies using 21-day-old weaned pigs fed 5% PEDv PCR+ plasma in a meal diet for 21 or 28 days post-weaning did not infect pigs with PEDv.
4: Spray-dried plasma contaminated post-processing with PEDv should survive through distribution until consumed by pigs.	4: PEDv inoculated on spray-dried plasma did not survive by: 7 days stored at 71°F (22°C) 14 days stored at 54°F (12°C) 21 days stored at 39°F (4°C)
5: Pigs in a PEDv-free region fed PEDv PCR+ plasma from the US should become infected with PEDv.	5: Millions of pigs in Brazil and Western Canada fed PEDv PCR+ porcine plasma imported from the US since last summer have not developed PEDv.
Conclusion: • Experimental results show that PCR+ spray-dried porcine plasma does not contain infective PEDv. • Infective PEDv reported by CFIA on samples of spray-dried porcine plasma collected from the field is likely the result of post-processing contamination.