Rate of PCV2 recombination not widely recognized

An interview with Meggan Bandrick, DVM, PhD Associate, Director Global Biologics Research, Zoetis
calendar icon 20 May 2021
clock icon 2 minute read
References
References
1 Franzo G, et al. Phylodynamic analysis of porcine circovirus type 2 reveals global waves of emerging genotypes and the circulation of recombinant forms. Mol Phylogenet Evol. 2016;100:269-280.
2 Neira V, et al. Genetic analysis of porcine circovirus type 2 from pigs affected with PMWS in Chile reveals intergenotypic recombination. Virol J. 2017;14(191).
3 Shao W, et al. Evolution of Influenza A Virus by Mutation and Re-Assortment. Int J Mol Sci. 2017 Aug;18(8):1650.
4 He C-Q, et al. Homologous recombination evidence in human and swine influenza A viruses. Virol. 2008 Oct;380(1):12-20.
5 Franzo G, et al. Phylodynamic analysis of porcine circovirus type 2.
6 Neira V, et al. Genetic analysis of porcine circovirus type 2.
7 Huang Y, et al. Evidence for different patterns of natural inter-genotype recombination between two PCV2 parental strains in the field. Virus Res. 2013 Jul;175(1):78-86.
8 Karuppannan A, et al. Porcine Circovirus Type 2 (PCV2) Vaccines in the Context of Current Molecular Epidemiology. Viruses. 2017 May; 9(5):99.
9 Salgado R, et al. Identification of an Emergent Porcine Circovirus-2 in Vaccinated Pigs from a Brazilian Farm during a Postweaning Multisystemic Wasting Syndrome Outbreak. Genome Announc. 2014 Mar-Apr; 2(2):e0016314.
10 Xiao C-T, et al. Complete Genome Sequence of a Novel Porcine Circovirus Type 2b Variant Present in Cases of Vaccine Failures in the United States. J Virol. 2012 Nov;86(22):12469.
11 Karuppannan A, et al. Porcine Circovirus Type 2 (PCV2) Vaccines.
12 Data on file, Study Report No. 16PRGBIO-01-01, Zoetis LLC.
13 Data on file, Study Report Zoetis WO1, EpiCC PCV2 Analysis, Zoetis LLC.
14 Data on file, Study Report Zoetis W02, EpiCC PCV2 Analysis, Zoetis LLC.

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